Stress increases the levels of catecholamines, neuropeptides, and cortisol that are higher in vitiligo patients [37–39] suggesting their role in the pathogenesis of vitiligo.
What causes vitiligo? Vitiligo is an autoimmune disease. This type of disease develops when your immune system attacks part of your own body. If you have vitiligo, your immune system attacks cells in your body called melanocytes. These are cells that make pigment.
The triggers, which range from sunburn to mechanical trauma and chemical exposures, ultimately cause an autoimmune response that targets melanocytes, driving progressive skin depigmentation.
To the best of our knowledge, vitamin D significantly affects melanocytes and keratinocytes. Studies suggest that vitamin D3 increases tyrosinase activity and melanogenesis in vitro [12], which may lead to repigmentation in vitiligo skin lesions.
Some food items like juicy fruits rich in vitamin C or ascorbic acid such as oranges and lemon, other fermented food items as curd, alcohol, Fish, red meat are to be avoided as they have harmful effect on vitiligo and can give rise to spreading of patches.
Vitiligo often starts as a pale patch of skin that gradually turns completely white. The centre of a patch may be white, with paler skin around it. If there are blood vessels under the skin, the patch may be slightly pink, rather than white. The edges of the patch may be smooth or irregular.
Many people who have vitiligo are often otherwise healthy. Even so, it's important to find a doctor like a dermatologist who knows about vitiligo. People who have vitiligo have a higher risk of getting some other medical conditions. You can also get painful sunburns on the skin that has lost color.
Vitiligo signs include: Patchy loss of skin color, which usually first appears on the hands, face, and areas around body openings and the genitals.
Several studies showed that vitiligo has been associated with autoimmune thyroid diseases, pernicious anemia, Addison's disease.
Avoid junk foods: Studies have shown that children who have a habit of eating a lot of junk are at a high risk of developing vitiligo. Also a lot of intake of chocolates, cheese, and coffee is also not good for patients with vitiligo.
Vitiligo is caused by partial or complete destruction of melanocytes in the affected skin area and influences the patient's quality of life. Besides physical involvement, vitiligo patients experience a high level of stress. Depression and Anxiety are common psychiatric disorders in vitiligo patients.
“Patients with sleep disorders may suffer the potential risk for vitiligo. Therefore, a bidirectional relationship exists between vitiligo and sleep disorders.”
Topical steroids. Topical steroids come as a cream or ointment you apply to your skin. They can sometimes stop the spread of the white patches and may restore some of your original skin colour.
Vitiligo is an idiopathic disorder of skin and hair characterized by melanin loss. Nonetheless thyroid disorder is a major cause of this pathology, other factors participate in its expression. Hormones such as, testosterone and estrogen have been suspected as drivers of this disorder.
Vitiligo — like many skin conditions — can be challenging to live with, mainly because of the way the skin looks. However, people with vitiligo are usually in good health and live normal lives. If it is not associated with symptoms that cause physical discomfort or complications, the condition may be left untreated.
Vitiligo is an autoimmune disease of the skin, which means that someone with vitiligo has an immune system that is malfunctioning in a small way. The normal role of the immune system is to protect you from infections and cancer.
The disease does not affect life expectancy. However, it can have a significant impact on quality of life, especially psychologically and be responsible for disorders such as depression and anxiety.
Segmental vitiligo is unique, even beyond the fact that it doesn't cross the midline. It spreads very quickly, faster than the other forms, but only for about 6 months (sometimes up to a year).
Research suggests that most people who develop vitiligo do so during childhood. As you age, Dr. Mohta says untreated vitiligo often progresses to involve the surrounding skin or create new patches of discoloration.
Potential triggers include sunburn, exposure to certain chemicals, and trauma or injury to the skin, according to the article in F1000 Research. These triggers can also prompt vitiligo to spread in people who already have the condition.
Moreover, people with vitiligo lack melanin, which is the body's natural protection from the sun, so sun exposure can be particularly dangerous. That's why it's vital that people with vitiligo use broad-spectrum sun protection with an SPF (sun protection factor) of 30 and above.
Vitamin B12 has been shown to be useful for repigmentation in patients suffering from vitiligo. Folic acid (or vitamin B9) has been proven to be significant for treating vitiligo.