The HPV test looks for the virus (human papillomavirus) that can cause cell changes on the cervix. The Pap test (or Pap smear) looks for precancers, cell changes on the cervix that might become cervical cancer if they are not treated appropriately.
About 5% of all Pap tests will be abnormal, meaning that the sample contains atypical cervical cells. However, the majority of these cells are not cancerous or even precancerous. An abnormal Pap test result does not mean cancer, but it does require follow-up to rule out the possibility of cancer.
A finding of cells that are cancerous (rather than precancerous) on a Pap test is rare, occurring in only 4.5 per 100,000 Pap tests [3]. If you have this result, you will need a biopsy of the cervix to confirm that cancer is present; this is usually performed during a colposcopy.
“I Received an Abnormal Pap Test. What's Next?” Your next step is usually a minor procedure called a colposcopy. This procedure is a visual examination of the cervix using a low-powered microscope used to find and then biopsy abnormal areas in your cervix that may lead to cervical cancer.
In most cases, an abnormal Pap test is a result of: A human papillomavirus (HPV) infection. A sexually transmitted infection (STI or STD), such as herpes or trichomoniasis. A bacterial or yeast infection.
ASC-US is the most common abnormal Pap test result. ASC-US stands for atypical squamous cells of undetermined significance. “Squamous” refers to the type of cells that make up the tissue that covers the cervix. LSIL—This means that the cervical cells show changes that are mildly abnormal.
HPV-related cancers often take years to develop after getting an HPV infection. Cervical cancer usually develops over 10 or more years. There can be a long interval between being infected with HPV, the development of abnormal cells on the cervix and the development of cervical cancer.
Most women will have at least one abnormal Pap smear result in their lifetime, with an overall average of 5% of all Pap tests coming back as “abnormal.” In most cases, the abnormal result is nothing to worry about, but it's important to follow up to make sure.
More than 14,000 Americans develop cervical cancer each year. However, cervical cancer is a treatable condition, and there is an excellent chance of cure if the cancer is found and treated in the early stages.
Whilst about 1 in 20 women will have a smear test result which is abnormal, only about 1 in 2000 will have cervical cancer.
Most people with HPV do not know they have the infection. They never develop symptoms or health problems from it. Some people find out they have HPV when they get genital warts. Women may find out they have HPV when they get an abnormal Pap test result (during cervical cancer screening).
The only cancer the Pap test screens for is cervical cancer. Since there is no simple and reliable way to screen for any gynecologic cancer except for cervical cancer, it is especially important to recognize warning signs, and learn what you can do to reduce your risk.
A Pap test is a simple screening test that can help prevent cancer of the cervix (cervical cancer). A Pap test looks for abnormal cell changes in the cervix. It does not test for other cancers in the reproductive organs or for sexually transmitted infections, such as chlamydia, gonorrhea or HIV.
A Pap smear is used to screen for cervical cancer. The Pap smear is usually done in conjunction with a pelvic exam. In women older than age 30, the Pap test may be combined with a test for human papillomavirus (HPV) — a common sexually transmitted infection that can cause cervical cancer.
Natural cervical cell changes (atrophic vaginitis) related to menopause can cause an abnormal Pap test. Usually cells return to normal on their own, after an infection has been treated or has resolved on its own.
Cervical cancer is most frequently diagnosed in women between the ages of 35 and 44 with the average age at diagnosis being 50 . It rarely develops in women younger than 20. Many older women do not realize that the risk of developing cervical cancer is still present as they age.
It is usually a slow-growing cancer and if caught early can be successfully treated. Routine Pap smears can detect early changes in the cells of the cervix allowing cervical cancer to be diagnosed early.
There is only two to five percent of the women who have a pap smear that has results come back abnormal. If you happen to fall into that group, you may be a bit nervous. This information will help you understand what it means to get an 'abnormal' test result on your pap smear.
Pap smear also helps in detecting or at least gives a clue to the presence of STIs such as trichomoniasis, Candida, Actinomyces, herpes simplex virus (HSV), cytomegalovirus, and human papillomavirus (HPV).
Most people with HPV — no matter what their gender is — don't have any symptoms. Sometimes HPV can cause warts on your penis or vulva and around your anus. Genital warts can cause irritation and discomfort, and you can pass the HPV that caused them to other people.
Signs of HPV
The most common are small, hard sores called warts, but not everyone who has HPV gets them. They may be raised, flat, or shaped like a cauliflower, and they can be different sizes. They can show up on your genital area or other places, depending on the type of the virus you have.
If left untreated, some strains of HPV can cause cellular changes in your body that lead to cancer. The most common type of cancer linked to HPV is cervical cancer, but HPV infection can also cause cancer of the vulva, vagina, penis, anus, or back of the throat. HPV is the leading cause of cervical cancer.