Document the acute clinical features of the reaction: rapidly developing, life‐threatening problems involving the airway (pharyngeal or laryngeal oedema), and/or breathing (bronchospasm with tachypnoea), and/or circulation (hypotension and/or tachycardia), and in most cases, associated skin and mucosal changes.
The Ring and Messmer scale
7, 10, 11 Grades I and II reactions are not life-threatening and are more likely to be non-allergic, although they may still be IgE-mediated. Grades III and IV are life-threatening conditions, also called 'anaphylaxis', which are usually IgE-mediated.
Signs and symptoms include: Skin reactions, including hives and itching and flushed or pale skin. Low blood pressure (hypotension) Constriction of the airways and a swollen tongue or throat, which can cause wheezing and trouble breathing.
Anaphylaxis is a sudden-onset, immediate reaction that implies a risk of death. Think of a "rule of 2's" for anaphylaxis implying that reactions usually begin within 2 minutes to 2 hours after injection, infusion, ingestion, contact, or inhalation.
Anaphylaxis is a severe, life-threatening, generalized or systemic rapid-onset hypersensitivity reaction (allergic or nonallergic). Anaphylactic shock is a severe rapidly progressing anaphylactic reaction (anaphylaxis) resulting in a life-threatening drop in blood pressure.
The most common symptoms of anaphylaxis are hives (urticaria) and swelling of the skin (angioedema), which occur in most cases. Respiratory symptoms occur frequently and are especially common in people who also have asthma or another chronic respiratory disease.
Check if it's anaphylaxis
They usually start within minutes of coming into contact with something you're allergic to, such as a food, medicine or insect sting. Symptoms include: swelling of your throat and tongue. difficulty breathing or breathing very fast.
swelling of lips, face, eyes. hives or welts appearing on the skin. tingling mouth. abdominal pain, vomiting (these are signs of anaphylaxis for insect allergy).
The first signs of an anaphylactic reaction may look like typical allergy symptoms: a runny nose or a skin rash. But within about 30 minutes, more serious signs appear. There is usually more than one of these: Coughing; wheezing; and pain, itching, or tightness in your chest.
Epinephrine — Epinephrine is the first and most important treatment for anaphylaxis, and it should be administered as soon as anaphylaxis is recognized to prevent the progression to life-threatening symptoms as described in the rapid overviews of the emergency management of anaphylaxis in adults (table 1) and children ...
Fullness or a "lump in the throat," persistent clearing of the throat, or difficulty breathing are all concerning symptoms of anaphylaxis and should be treated aggressively. Other respiratory symptoms include hoarseness, wheezing, and stridor.
Definition of Anaphylaxis
It can be mild, moderate to severe, or severe. Most cases are mild but any anaphylaxis has the potential to become life-threatening. Anaphylaxis develops rapidly, usually reaching peak severity within 5 to 30 minutes, and may, rarely, last for several days.
Some people may experience a mild anaphylactic reaction and not go into shock. For example, they may experience hives and difficulty breathing after accidentally eating a food allergen. They may not see a sudden drop in blood pressure that leads to anaphylactic shock.
Allergic reactions are common in children. Most reactions are mild. A severe allergic reaction (i.e. anaphylaxis) involves a person's breathing and/or circulation. Anaphylaxis is the most severe form of an allergic reaction and is life threatening.
Anaphylaxis usually begins with severe itchiness in the eyes or face. Within a few minutes, you may start experiencing more severe symptoms, including: Swelling, which may cause swallowing and breathing difficulties.
Q: What do you do if someone goes into anaphylactic shock without an EpiPen? A: Make sure that you've called 911. If antihistamines are on-hand, these can be administered and may provide some relief, but antihistamines are never a suitable medication for fully treating anaphylactic shock.
Epinephrine (adrenaline) to reduce the body's allergic response. Oxygen, to help you breathe. Intravenous (IV) antihistamines and cortisone to reduce inflammation of the air passages and improve breathing.
In some cases, people won't experience the most severe symptoms of anaphylaxis, such as difficulty breathing, and thus decide not to seek medical care.
Drug-induced anaphylaxis is the most common cause of fatal anaphylaxis in most regions where data are available, but is rare relative to nonanaphylactic causes of mortality.
Antihistamines DO NOT stop the progression of an anaphylaxis. Antihistamines only help to decrease itching and reduce mild/moderate swelling of the face, lips and eyes. DO NOT SHOWER as this may contribute to a drop in blood pressure which can escalate the severity of an allergic reaction.
Laying the person flat will help blood flow to the heart which improves blood pressure, whilst standing can make anaphylaxis worse by causing blood pressure to drop.