Alcoholic liver disease is defined by three stages of liver damage following chronic heavy alcohol consumption:
It takes upwards of ten years for alcohol-related liver disease to progress from fatty liver through fibrosis to cirrhosis to acute on chronic liver failure. This process is silent and symptom free and can easily be missed in primary care, usually presenting with advanced cirrhosis.
Cirrhosis is the final stage of alcohol-related liver disease. It usually happens after many years of heavy drinking.
The first stage of alcoholic liver disease is hepatic steatosis, which involves the accumulation of small fat droplets under liver cells approaching the portal tracts. More advanced disease is characterized by marked steatosis, hepatocellular necrosis, and acute inflammation, known as alcoholic hepatitis.
Fatty liver disease is reversible. If you stop drinking alcohol for 2 weeks, your liver should return to normal.
The life expectancy of a person with alcoholic liver disease reduces dramatically as the condition progresses. On average, 1 in 3 people with the most advanced stage of liver disease and cirrhosis are still alive after 2 years. When the body can compensate and manage cirrhosis, the typical lifespan is 6–12 years.
Even after years of heavy alcohol use, the liver has a remarkable regenerative capacity and, following alcohol removal, can recover a significant portion of its original mass and function.
Drinking a bottle of wine per day is not considered healthy by most standards. However, when does it morph from a regular, innocent occurrence into alcohol use disorder (AUD) or alcoholism? First, it's important to note that building tolerance in order to drink an entire bottle of wine is a definitive red flag.
This amount corresponds to an average daily intake of 30 grams of undiluted alcohol for 10 years. Heavy alcoholics consuming at least 80 g of alcohol per day for more than 10 years will develop liver disease at a rate of nearly 100%.
Patients with compensated cirrhosis have a median survival that may extend beyond 12 years. Patients with decompensated cirrhosis have a worse prognosis than do those with compensated cirrhosis; the average survival without transplantation is approximately two years [13,14].
Although the overall leading cause of death in patients with cirrhosis is liver-related, the most common causes of mortality in patients with NAFLD cirrhosis is non-hepatic malignancy, cerebrovascular disease, and diabetes.
If you have fatty liver disease, the damage may be reversed if you abstain from alcohol for a period of time (this could be months or years). After this point, it's usually safe to start drinking again if you stick to the NHS guidelines on alcohol units. However, it's important to check with your doctor first.
The liver's job is to break down alcohol. If you drink more than it can process, it can become badly damaged. Fatty liver can happen in anyone who drinks a lot. Alcoholic hepatitis and alcoholic cirrhosis are linked to the long-term alcohol abuse seen in alcoholics.
Over time, excessive alcohol use can lead to the development of chronic diseases and other serious problems including: High blood pressure, heart disease, stroke, liver disease, and digestive problems. Cancer of the breast, mouth, throat, esophagus, voice box, liver, colon, and rectum.
The short answer is yes: blood testing can show heavy alcohol use. However, timing plays a significant role in the accuracy of blood alcohol testing. In a typical situation, blood alcohol tests are only accurate six to 12 hours after someone consumes their last beverage.
Nausea. Vomiting. A general sense of feeling unwell (malaise) Disorientation or confusion.
Liver failure occurs when your liver isn't working well enough to perform its functions (for example, manufacturing bile and ridding your body of harmful substances). Symptoms include nausea, loss of appetite, and blood in the stool. Treatments include avoiding alcohol and avoiding certain foods.
The liver is part of the body's natural detoxification system, which helps filter out toxins. Foods that support liver health include berries, cruciferous vegetables, beans, whole grains, nuts, and fatty fish. Coffee and green tea contain antioxidants that are helpful for liver health.