The most common reason for a negative Pap test with a positive HPV result is that the patient has an HPV infection, but the infection is not causing any cellular abnormalities. Cellular abnormalities caused by HPV can be quite focal on the cervix, while the HPV infection can be more widespread.
A positive test result means that you have a type of high-risk HPV that's linked to cervical cancer. It doesn't mean that you have cervical cancer now, but it's a warning sign that cervical cancer could develop in the future.
In fact, many women with HPV will never have an abnormal pap smear. That being said, routine screening with your provider is the only way to follow any changes to the cervix that could lead to cervical cancer.
HPV positive: no abnormal cells
If none are found, your result will say you have HPV , but no abnormal cells. We will ask you to come for screening again sooner than usual (your result letter will explain when). This is so we can check if your immune system has got rid of the HPV (this happens in most cases).
About 10% of women with HPV infection on their cervix will develop long-lasting HPV infections that put them at risk for cervical cancer. Similarly, when high-risk HPV lingers and infects the cells of the vulva, vagina, penis, or anus, it can cause cell changes called precancers.
Research has found that it can take 10 to 20 years, or even longer, for HPV-infected cervical cells to develop into a cancerous tumor. Among women whose cervical cells are infected with high-risk HPV, several factors increase the chance that the infection will be long lasting and lead to precancerous cervical cells.
If you got a positive HPV test and your Pap test was abnormal, your doctor will probably follow up with a colposcopy. Try to see a physician who specializes in this procedure. During a colposcopy, your doctor will look more closely at the cervix, vagina or vulva with a special microscope called a colposcope.
In most cases (9 out of 10), HPV goes away on its own within two years without health problems. But when HPV does not go away, it can cause health problems like genital warts and cancer.
Q: How long after exposure does it usually take for something to be detectable? A: Changes consistent with HPV can usually be detected within 3-6 months after exposure to the infection.
HPV-related cancers often take years to develop after getting an HPV infection. Cervical cancer usually develops over 10 or more years. There can be a long interval between being infected with HPV, the development of abnormal cells on the cervix and the development of cervical cancer.
Anyone who has had sex can get HPV, even if it was only with only one person, but infections are more likely in people who have had many sex partners. Even if a person delays sexual activity until marriage, or only has one partner, they are still at risk of HPV infection if their partner has been exposed.
HPV testing can be performed for women with a Pap test (commonly known as a Pap smear), which is a screening test for cervical cancer. HPV testing is only available for women, and it can determine if HPV is present. If present, the test can determine whether the HPV is a low- or a high-risk type.
But even after the warts are gone, HPV might still be active in the body. That means it can spread to someone else through sex or close sexual contact and cause warts in that person. It's hard to know when people are no longer contagious, because there's no blood test that looks for HPV.
An HPV test finds high-risk types of HPV on your cervix that can possibly lead to cancer. Your doctor can tell you which tests you need and how often you should get them. There isn't a test for high-risk HPV in the vulva, penis, anus, or throat, and HPV itself doesn't have any symptoms.
If you test positive for HPV 16/18, you will need to have a colposcopy. If you test positive for HPV (but did not have genotyping performed or had genotyping and tested negative for 16/18), you will likely have a colposcopy.
You'll be referred for a colposcopy if your cervical screening test reveals cervical cell changes, or symptoms such as unexplained pelvic pain or vaginal bleeding need to be investigated. It will usually be carried out in the outpatients department of your local hospital.
What causes an abnormal Pap test? Most abnormal Pap tests are caused by HPV infections. Other types of infection—such as those caused by bacteria, yeast, or protozoa (Trichomonas)—sometimes lead to minor changes on a Pap test called atypical squamous cells.
Pap Results Are Often Inaccurate
Sometimes these false positive Paps can be explained by a recent vaginal infection, or trauma to the cervix due to douching, tampons, or intercourse; sometimes the false positives just represent an inherent limitation of the test.
Advanced cervical cancer may mean you feel sick or cause other effects that can make you lose your appetite. You may lose weight anyway because of the cancer and not feel like eating as much. Making some simple changes to your diet may help with feeling sick and getting your appetite back.
Cervical cancer symptoms include vaginal bleeding that is unusual for you, changes to vaginal discharge, discomfort during sex and pain in your lower back or pelvis. If you have symptoms, you should contact your GP.
Almost all cervical cancer is caused by HPV. Some cancers of the vulva, vagina, penis, anus, and oropharynx (back of the throat, including the base of the tongue and tonsils) are also caused by HPV.