The data before PSM in this study also obtained the similar result that there was no statistical difference in the early abortion rate between the PCOS group and non-PCOS group, but the overall late abortion rate was significantly higher in the PCOS group (5.69%) as compared with the non-PCOS group (2.52%).
In addition, once a pregnancy is achieved, spontaneous miscarriages can also be observed more frequently in PCOS patients; the risk has been reported to range from 42 to 73% [2]. Miscarriage is among the most common complications during pregnancy and can be sporadic or recurrent [4].
The risk of spontaneous abortion in patients with polycystic ovary syndrome (PCOS) undergoing assisted reproductive treatment (ART) is higher than that in patients without PCOS, however, no definitive risk factors have been confirmed to associate with the high spontaneous abortion rate in PCOS patients undergoing ART.
On average, women with PCOS take longer to fall pregnant than other women. This can be because they have irregular periods which means that they don't ovulate every month. Also, being overweight reduces fertility and can contribute to women with PCOS taking longer to conceive.
It's also important to keep in mind that just because a woman has PCOS doesn't mean that she also has infertility. As one study points out, 70 to 80 percent of these women are infertile. (5) That leaves up to 30 percent of women who may become pregnant on their own without the use of fertility treatments.
Give yourself the best possible chance
Wondering what the best age to get pregnant with PCOS is? Generally speaking, women under the age of 35 have about a 30% chance of conceiving in the first month of trying and around an 85% chance in the first year.
Polycystic Ovary Syndrome (PCOS) can cause recurrent miscarriages because of high levels of testosterone. PCOS-related insulin resistance can also affect the lining of your uterus. Bacterial infections can live in your or your partner's genital tracts.
Some of the key factors include: Age: As we've mentioned earlier, fertility naturally declines with age, and this is true for women with or without PCOS. Women in their late 20s and early 30s tend to have the highest fertility rates, with a more rapid decline after the age of 35.
The best way to prevent miscarriage in women with polycystic ovarian syndrome (PCOS) is to normalize hormone levels to improve ovulation, and normalize blood glucose and androgen levels. Recently, more doctors are prescribing the drug metformin to help with this.
Pregnant women with PCOS experience a higher incidence of perinatal morbidity from gestational diabetes, pregnancy-induced hypertension, and preeclampsia. Their babies are at an increased risk of neonatal complications, such as preterm birth and admission at a neonatal intensive care unit.
PCOS after pregnancy
It is important to remember that some of the symptoms of PCOS, such as hormonal imbalance and associated weight gain, can return and even worsen after pregnancy – and that being pregnant and successfully giving birth does not mean that PCOS has gone away.
As previously stated, the shape of a PCOS belly differs from other types of weight gain. It often appears large and bloated but can also be small and round, depending on genetics and other factors. The PCOS belly involves the accumulation of visceral fat in the lower abdomen and typically feels firm to the touch.
For women with PCOS who are overweight or obese, a modest weight loss sometimes results in more regular ovulation, which increases the chance of pregnancy. For those who know they ovulate, having sex during the “fertile window” (the five days leading up to and including ovulation) boosts the chance of conception.
Fortunately, with lifestyle changes or infertility treatment, most people with PCOS can become pregnant. Talk to your doctor or fertility specialist for individual advice for your situation.
When the congenital abnormalities were analysed by the type of malformation, cardiovascular and urogenital malformations were more common in the offspring of women with PCOS; cardiovascular (1.5% compared with 1.0%, OR 1.37, 95% CI 1.01–1.87) and urogenital defects (2.0% compared with 1.4% OR 1.36, 95% CI 1.03–1.81).
Women with PCOS may be more likely to have multiples (twins, or more). One study found that while the multiple pregnancy rate is 1.1% in the average population, it is 9.1% for women with PCOS patients.
However, in older “lean” PCOS women, who by this time usually have become hypo-androgenic, egg quality is, indeed, negatively affected, unless androgen levels are appropriately pre-supplemented, starting at least 6-8 weeks prior to IVF cycle start.
A HEALTHY PREGNANCY IS POSSIBLE
Women who get pregnant after 30 or who have PCOS will have more risks associated with pregnancy. One of these risks is gestational diabetes. However, there are steps a woman can take to prevent or manage gestational diabetes and have a healthy pregnancy.
If you haven't been diagnosed with PCOS but have had a miscarriage or multiple miscarriages, you should be evaluated for PCOS, as one study found that PCOS was present in approximately 40% to 80% of women with recurrent miscarriages.
Use of metformin throughout pregnancy in women with PCOS has shown to reduce the rates of early pregnancy loss, preterm labor, and prevention of fetal growth restriction.
PCOS should not really affect the results of your pregnancy test. False negative test results are usually caused by low levels of human chorionic gonadotropin (HCG).
In the study, 5 mg of folate supplementation, compared with 1 mg and a placebo, resulted in better glucose metabolism and better cholesterol lab values in women with PCOS. The average prenatal vitamin has between 600-1000mcg (1 mg) of folic acid or folate, so to reach 5 mg another supplement may be needed.
Lea Michele
The Glee star has opened up about being diagnosed with PCOS after experiencing severe acne and fluctuating weight. “The side effects [of PCOS] can be brutal — like weight gain and bad skin,” Lea shared with Health. “I went to a great doctor, and the minute she looked at me, she was like, 'Oh, you have PCOS.