Much like sildenafil, tadalafil is the active, unbranded medicine used to treat erectile dysfunction. Tadalafil starts to work within 30 minutes of taking the medication and can be active for up to 36 hours, which allows for more spontaneity. Unlike sildenafil, you can take tadalafil with or without food [2].
The 'as required' Tadalafil (generic Cialis) has an advantage over Sildenafil in that it lasts a lot longer – up to 36 hours (compared with 4-5 hours for Sildenafil). Some men prefer this as it allows for more spontaneity.
The number one difference between the two drugs is how long they last. Tadalafil can last up to 36-hours, which means it will treat erectile dysfunction anytime within the 36-hour timeframe. While contender Sildenafil typically only lasts around 4 to 6 hours.
You shouldn't take Cialis (tadalafil) and Viagra (sildenafil citrate) together to help with treating erectile dysfunction (ED). It's also typically recommended that you take one or the other shortly before sex, but not daily or on a regular schedule. These ED medications only work if you're already aroused.
Conclusion. A daily dose of 5mg tadalafil can be safely used in the treatment of erectile dysfunction and LUTS, that prolongs the ejaculatory latency time.
Without physical action to the penis, such as that occurring during sexual intercourse, tadalafil will not work to cause an erection. Tadalafil is also used to treat men who have signs and symptoms of benign prostatic hyperplasia (BPH). BPH is caused by an enlarged prostate.
Headache, stomach upset, back pain, muscle pain, stuffy nose, flushing, or dizziness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.
If you are taking tadalafil for prostate enlargement, you can take your tablet in the morning or evening, but it's best to take it at the same time each day.
Conclusion: Tadalafil at doses of 5, 10, or 20mg taken as needed up to once daily for 18 to 24 months was safe and well tolerated. These findings support the long-term use of tadalafil in the clinical management of erectile dysfunction.
Adults—40 milligrams (mg) (two 20 mg tablets) taken once a day. Take both tablets at the same time each day. Do not divide the 40 mg dose. Your doctor may adjust your dose as needed.
There are several reasons Viagra and other ED drugs might not work effectively as treatments for erectile dysfunction. These include using Viagra incorrectly, taking a low dose of Viagra and using Viagra to treat ED that's caused by something other than poor blood flow.
The typical maximum dose of Cialis for ED is 20 mg once a day. If a doctor has prescribed Cialis for pulmonary arterial hypertension, you may be advised to take two 20-mg doses a day. But taking that much of the medication should be done only under a doctor's guidance.
Tadalafil (Cialis) is available in generic and brand versions in several doses as an oral tablet. You can take Cialis as needed or once a day, depending on the dose and how it's prescribed. Cialis takes from 30 minutes to 2 hours to take effect. It can last up to 36 hours.
Vardenafil (Levitra) is almost 10 times more biochemically potent than sildenafil, therefore a lower dose is needed to facilitate the penile erection, potentially resulting in less side effects. Selectivity is the ability of the drug to attach to the specific enzyme PDE 5 found in penile tissues.
Dosage and strength for erectile dysfunction
Sildenafil tablets for erectile dysfunction come in different strengths ranging from 25mg to 100mg. The usual dose is 50mg, when you need it. Do not take it more than once a day. The dose can be increased to 100mg or decreased to 25mg depending on its effect.
Cialis taken as needed
But if this dose doesn't work for you, your doctor may have you take two 5 mg tablets of Cialis at once. This will increase the dose back to 10 mg. If the 10-mg dose of Cialis isn't working well enough, your doctor may increase it to 20 mg.
Like all PDE5 inhibitors, tadalafil requires sexual stimulation to work – ie: you only get an erection when you want to. Some men report having an erection as quickly as 16 minutes. Most men feel the benefit of tadalafil after 30 minutes.
Currently, there is no scientific evidence that sildenafil, tadalafil or any other medications used to treat erectile dysfunction are physically addictive.
You may be more likely to experience symptoms such as dizziness, lightheadedness, fainting, flushing, headache, and heart palpitations. You should avoid or limit the use of alcohol while being treated with tadalafil, and use caution when getting up from a sitting or lying position.
The maximum recommended dosage of Cialis is 20 mg once per day. Taking a dose of Cialis that's higher than recommended could increase your risk for side effects. These can include serious side effects such as drops in blood pressure or priapism (a painful erection that won't go away).
Women preferring tadalafil reported feeling more relaxed, experiencing less pressure, and enjoying a more natural or spontaneous sexual experience as reasons for their choice.
Who should not take Cialis? Cialis should not be used by patients taking nitrates (such as nitroglycerin tablets or patches) because the combination of these with Cialis could significantly lower blood pressure and lead to fainting or even death in some men.
Hepatotoxicity. Despite fairly extensive use, tadalafil has been linked to only rare reports of serum aminotransferase elevations and clinically apparent liver injury. In a single case report, tadalafil was linked to cholestatic hepatitis arising within a few days of starting the medication.
Tolerance to the therapeutic effect of tadalafil does not occur during 6 months of treatment: A randomized, double-blind, placebo-controlled study in men with erectile dysfunction. J Sex Med.
Cialis usually takes about 30 minutes to take effect with sexual stimulation and its effect lasts for up to 36 hours, which is why it is sometimes referred to as a “weekend pill”.