In September 2021, the Therapeutic Goods Administration approved dapagliflozin for treatment of CKD to reduce the risk of progressive decline in kidney function in adults with proteinuric CKD (stage 2, 3 or 4 and urine ACR≥ 30 mg/g) (TGA 2021).
The Australian Government will expand the PBS listing of dapagliflozin from 1 September 2022. Chronic kidney disease is estimated to cost the Australian health system approximately $5.1 billion per year and access to dapagliflozin will help reduce the risk of progressive decline in kidney function.
20 January 2023 - The U.S. Food and Drug Administration (FDA) has accepted a supplemental New Drug Application (sNDA) for Jardiance® (empagliflozin) tablets, which is being investigated as a potential treatment to reduce the risk of kidney disease progression and cardiovascular death in adults with chronic kidney ...
Finerenone (Non-steroidal mineralocorticoid antagonist (MRA)) Finerenone is FDA-approved1 for those with type 2 diabetes-associated kidney disease who have an eGFR above 25 and a urine-albumin creatinine ratio above 30. It may improve kidney and heart outcomes by preventing fibrosis or scarring of the kidneys.
A recent study has detected antibodies that target nephrin, which is a protein expressed in the kidney's specialized cells called podocytes that maintains the glomerular filtration barriers. This discovery has been regarded as a step forward in kidney research, particularly in minimal change disease studies.
Eat a kidney-friendly diet and exercise regularly.
Regular exercise and maintaining a healthy weight are also effective ways to help manage your disease progression.
Acute kidney failure requires immediate treatment. The good news is that acute kidney failure can often be reversed. The kidneys usually start working again within several weeks to months after the underlying cause has been treated. Dialysis is needed until then.
People with CKD have greater requirements for some water soluble vitamins. Special renal vitamins are usually prescribed to provide extra water soluble vitamins needed. Renal vitamins contain vitamins B1, B2, B6, B12, folic acid, niacin, pantothenic acid, biotin and a small dose of vitamin C.
New drug for chronic kidney disease (CKD) in people with type 2 diabetes. The National Institute for Health and Care Excellence (NICE) has approved a new drug for chronic kidney disease in people with type 2 diabetes. The medication is called finerenone (also known as Kerendia).
While it's not possible to reverse kidney damage, you can take steps to slow it down. Taking prescribed medicine, being physically active, and eating well will help. You'll also feel better and improve your overall well-being.
The WAK™ was developed after a decade of research and at a cost of over $30 million. The device has been clinically tested in Europe, and it has the potential to dramatically reduce the costs of treatment for those suffering from kidney disease.
The bottom line
NSAIDs, diuretics, and ACE inhibitors are potential drugs that cause kidney damage. Certain medications administered in hospital settings, like aminoglycoside antibiotics and vancomycin, can also damage the kidneys.
Acute kidney failure is often called acute kidney injury. Acute kidney failure (injury) is usually short term and your kidney function will recover over time. Chronic kidney failure is often called chronic kidney disease. Chronic kidney failure can be treated with dialysis, a kidney transplant or supportive care.
ACE inhibitors (Angiotensin-converting enzyme inhibitors): medicines that lower blood pressure. They widen your blood vessels, help your kidneys get rid of extra water and lower the levels of hormones that raise blood pressure.
The lowdown
While plain water is the best drink for your kidneys, other fluids are perfectly acceptable, including coffee, green tea, low-potassium juices, and infused water. Avoid sweetened, carbonated beverages and coconut water.
Water: Water is simply the best drink you can have! Water is a zero-calorie, perfectly hydrating, cheap drink. If you are in the earlier stages of kidney disease, choosing water most of the time to quench your thirst will keep your body and kidneys functioning well.
Lemon Juice
Lemon juice is naturally acidic and increases citrate levels in urine, hence discouraging the formation of kidney stones. Lemon juice also filters blood and flushes out wastes and other toxins.
The calcium antagonistic effect of magnesium is also important for reducing the risk of kidney stones, and silent kidney stones significantly increase the risk of kidney failure. As low magnesium intake will reduce the urinary magnesium concentration, the beneficial effect of magnesium on stone formation is hampered.
03/5How turmeric affects kidneys? This is because curcumin in turmeric has high amounts of oxalates that can increase the risk of kidney stones and interfere with the functioning of this vital organ. In addition, curcumin has a hot potency which is often associated with diarrhea, indigestion, among other things.
Eating Processed Foods
Processed foods are significant sources of sodium and phosphorus. Many people who have kidney disease need to limit phosphorus in their diets. Some studies have shown that high phosphorus intake from processed foods in people without kidney disease may be harmful to their kidneys and bones.
When kidneys are failing, the increased concentration and accumulation of substances in urine lead to a darker color which may be brown, red or purple. The color change is due to abnormal protein or sugar, high levels of red and white blood cells, and high numbers of tube-shaped particles called cellular casts.