Sleep-promoting cells within the hypothalamus and the brain stem produce a brain chemical called GABA, which acts to reduce the activity of arousal centers in the hypothalamus and the brain stem.
Physical health conditions
Insomnia can also be caused by underlying physical conditions, including: heart conditions – such as angina or heart failure. respiratory conditions – such as chronic obstructive pulmonary disease (COPD) or asthma. neurological conditions – such as Alzheimer's disease or Parkinson's disease.
The levels of melatonin in the body normally increase after darkness, which makes you feel drowsy. The change in melatonin during the sleep/wake cycle reflects circadian rhythms. During sleep, the hypothalamus also controls changes in body temperature and blood pressure.
You may be accruing sleep debt due to circadian misalignment, or perhaps low sleep efficiency has you believing that you're getting more sleep than you are. It's also possible that a health condition is causing sleep disturbances and leading to excessive daytime sleepiness.
Melatonin is a hormone that your brain produces in response to darkness. It helps with the timing of your circadian rhythms (24-hour internal clock) and with sleep. Being exposed to light at night can block melatonin production.
Many cases of tiredness are due to stress, not enough sleep, poor diet and other lifestyle factors. Try these self-help tips to restore your energy levels. If you feel you're suffering from fatigue, which is an overwhelming tiredness that isn't relieved by rest and sleep, you may have an underlying medical condition.
Vitamin B12 Deficiency: A Rare Cause of Excessive Daytime Sleepiness.
Oversleeping is associated with many health problems, including: Type 2 diabetes. Heart disease. Obesity.
Too much sleep — as well as not enough sleep — raises the risk of chronic diseases, such as coronary heart disease, diabetes, anxiety and obesity in adults age 45 and older. Sleeping too much puts you at greater risk of coronary heart disease, stroke and diabetes than sleeping too little.
Abstract: Sleep disturbance is a common feature of chronic liver disease (CLD) with impact on health-related quality of life; 60–80% of patients with CLD report subjective poor sleep; frequent presentations of sleep disturbance include insomnia, reduced sleep efficiency, increased sleep latency, reduced time in rapid ...
Sleep–wake disturbances are common in liver cirrhosis and associated with impaired quality of life. The most common abnormalities are insomnia (difficulties falling asleep and maintaining sleep, or unrefreshing sleep), excessive daytime sleepiness, and sleep–wake inversion (disturbances of circadian rhythmicity).
Insomnia is common in most cancers but appears particularly so in lung, breast, and head and neck tumors. Older women seem most susceptible. Insomnia not only affects patients with cancer but also caregivers and families.
Most likely, you're still tired after 8 hours of sleep because you don't know your sleep need, you're getting less sleep than you think, you've got sleep debt, or you're out of sync with your circadian rhythm.
It could be due to poor sleep quality, lifestyle factors such as stress, poor diet, and lack of exercise or an underlying health condition. It is also possible that you may not be getting enough deep sleep or REM sleep, which can leave you feeling tired even after a full night's sleep.
Vitamin B12
Vitamin B12 is essential for the production of red blood cells and DNA. It is also essential for the functioning of the nervous system. When your body does not receive enough vitamin B12 you may feel fatigued and tired all the time.
The two most likely reasons you're always so tired no matter how much sleep you get are you've got high sleep debt or you're not living in sync with your circadian rhythm. You may also feel sleepy if you're ill, pregnant, or you've got a medical condition like anemia or diabetes.
Mental laziness and lack of motivation can also be caused by one simple problem: not having enough exercise and nutrients in the body. One should consider eating healthy food high in protein, such as green, leafy vegetables, and fatty fish. Research also suggests eating berries and walnuts and drinking coffee or tea.
Some conditions that cause fatigue include thyroid disorders, iron deficiency anemia, diabetes, chronic fatigue syndrome, and COVID-19. Some other causes of fatigue may involve your diet, sleep, and levels of stress. Lifestyle changes can often improve feelings of fatigue in these situations.
A cancer that affects your hormone levels could cause fatigue. Certain cancers such as breast and prostate cancer can change the levels of hormones in your body. This can cause a number of side effects including fatigue. People with advanced cancer are more likely to have fatigue than those with earlier staged cancer.
Sleep disturbances such as insomnia following pancreatic cancer surgery are highly prevalent.
Malignant brain tumors are among the most aggressive human neoplasms. One of the most common and severe symptoms that patients with these malignancies experience is sleep disruption.