The first organ system to “close down” is the digestive system. Digestion is a lot of work! In the last few weeks, there is really no need to process food to build new cells. That energy needs to go elsewhere.
The body attempts to protect the brain, says Zucker, by shutting down the most metabolically intense functions first, like digestion, resulting in diarrhea. "The brain is relatively protected, but eventually we worry about neuronal death and brain matter loss," she says.
The First Phase of Starvation
At first, glycogen is broken down into glucose. Only enough glycogen; however, is stored in the person's liver to last a few hours. After that period of time, blood glucose levels are maintained by the breakdown of fats and proteins. Fats are decomposed into glycerol and fatty acids.
As a result of discontinuing eating, patients can die in as early as a few days. For most people, this period without food usually lasts about 10 days, but in rare instances, it can last several weeks.
Not eating for long duration might also cause acute gastritis (a condition where the lining of the stomach is inflamed) resulting in liver or kidney failure and eventual shutdown of all organs.
The body needs the nutrients in food to survive. Without them, it will start to break down its own tissue to use as food. Starvation affects all of the body's systems and processes. It is difficult to determine how long someone can go without food, but experts believe that it is between 1 and 2 months.
Organ failure symptoms include low grade fever, tachycardia, and tachypnea in the first 24 hours. Within the following 24-72 hours, lung failure may set in. This can be followed by bacteremia, as well as renal, intestinal, and liver failure.
Without any food, humans usually die in around 2 months. There was a surprising case when someone survived 382 days. Lean people can usually survive with a loss of up to 18% of their body mass. Obese people can tolerate more, possibly over 20%.
Hunger hormone
The brain triggers the release of a hormone called ghrelin in response to an empty stomach or in anticipation of the next meal. Ghrelin signals the body to release stomach acids to digest food. If food is not consumed, the stomach acids begin to attack the lining of the stomach, causing hunger pains.
According to the USDA, there is a strong connection between hunger and chronic diseases like high blood pressure, heart disease, and diabetes. In fact, 58% of the households that receive food from the Feeding America network have one member with high blood pressure.
Starvation. When the body is deprived of nourishment for an extended period of time, it goes into “survival mode.” The first priority for survival is to provide enough glucose or fuel for the brain. The second priority is the conservation of amino acids for proteins.
What happens when someone dies? In time, the heart stops and they stop breathing. Within a few minutes, their brain stops functioning entirely and their skin starts to cool. At this point, they have died.
The heart and lungs are generally the last organs to shut down when you die. The heartbeat and breathing patterns become irregular as they progressively slow down and fade away.
This difficult time may be complicated by a phenomenon known as the surge before death, or terminal lucidity, which can happen days, hours, or even minutes before a person's passing. Often occurring abruptly, this period of increased energy and alertness may give families false hope that their loved ones will recover.
Some people experience a brief surge in energy in the hours or days before death. This may last from a few minutes to several hours. During this time, your loved one may talk more, be interested in engaging in conversation, or interested in eating or drinking.
There are three main stages of dying: the early stage, the middle stage, and the last stage. These are marked by various changes in responsiveness and functioning. However, it is important to keep mind that the timing of each stage and the symptoms experienced can vary from person to person.
The end-of-life period—when body systems shut down and death is imminent—typically lasts from a matter of days to a couple of weeks. Some patients die gently and tranquilly, while others seem to fight the inevitable. Reassuring your loved one it is okay to die can help both of you through this process.
During death, your body's vital functions stop entirely. Your heart no longer beats, your breath stops and your brain stops functioning. Studies suggest that brain activity may continue several minutes after a person has been declared dead. Still, brain activity isn't the same as consciousness or awareness.
The brain and nerve cells require a constant supply of oxygen and will die within a few minutes, once you stop breathing. The next to go will be the heart, followed by the liver, then the kidneys and pancreas, which can last for about an hour. Skin, tendons, heart valves and corneas will still be alive after a day.
In most cases, when a patient is receiving the care and support of hospice, they will not experience pain during the dying process. Instead, their body will naturally begin to shut down. They will begin to have a decreased desire to eat and drink and will start to sleep more.
Restlessness, agitation, and delirium are often the result of organ systems shutting down. Distressing as they may be to witness, they are normal to the dying process.