Therefore, if you have been around rodents and have symptoms of fever, deep muscle aches, and severe shortness of breath, see your doctor immediately. Be sure to tell your doctor that you have been around rodents—this will alert your physician to look closely for any rodent-carried disease, such as
If there is a high degree of suspicion of HPS, patients should be immediately transferred to an emergency department or intensive care unit (ICU) for close monitoring and care. Patients presenting with fulminant illness due to HPS have a poor prognosis despite ICU care.
As the illness progresses, the main symptom of hantavirus infection is difficulty in breathing, which is caused by fluid build-up in the lungs, and which quickly progresses to an inability to breathe. Infected people sometimes die of respiratory failure or shock.
Early symptoms include fatigue, fever and muscle aches, especially in the large muscle groups—thighs, hips, back, and sometimes shoulders. These symptoms are universal. There may also be headaches, dizziness, chills, and abdominal problems, such as nausea, vomiting, diarrhea, and abdominal pain.
People who are ill with hantavirus pulmonary syndrome and do not get help quickly may die. Those that survive recover quickly, though full recovery often takes several months.
Hantavirus infection can have no symptoms or cause mild to severe illness. Fever is the most common symptom in all three types of disease and lasts about 3-7 days.
When to see a doctor. The signs and symptoms of hantavirus pulmonary syndrome can worsen suddenly and may quickly become life-threatening. If you have flu-like symptoms that progressively worsen over a few days, see your health care provider. Get immediate medical care if you have trouble breathing.
HCPS, also known as hantavirus pulmonary syndrome (HPS), is a febrile illness characterized by respiratory failure with diffuse interstitial edema. The illness has three distinct phases: the prodrome, cardiopulmonary phase, and the convalescent phase.
The hantavirus can cause hantavirus pulmonary syndrome (HPS) in people. HPS is a rare but serious disease that initially causes flu-like symptoms. As the condition progresses and affects other organs, you may have trouble breathing and your heartbeat may get faster. HPS can be deadly without proper treatment.
Fatality rates may reach up to 60%. There is no available treatment. Early diagnostic may reduce fatality rates by half. It can be prevented by reducing contact with rodents and their excrement, as well as through hygienic practices to prevent rodent infestations in the home, workplace and recreation areas.
Immunohistochemistry (IHC) IHC testing of formalin-fixed tissues with specific monoclonal and polyclonal antibodies can be used to detect hantavirus antigens and has proven to be a sensitive method for laboratory confirmation of hantaviral infections.
In the year 2020, 833 cases of hantavirus infection had been reported, with 35% mortality rate in the US [8].
Hantavirus antibody-positive rodents have been found across Australia although, to date, there are no reports of infections in humans. This could be due to misdiagnosis clinically and/or inadequate laboratory technique/skills.
There is no specific treatment, cure, or vaccine for hantavirus infection. However, we do know that if infected individuals are recognized early and receive medical care in an intensive care unit, they may do better.
Any man, woman, or child who is around mice or rats that carry harmful hantaviruses can get HPS. You do not have to already be sick to be at risk for HPS. Healthy people have become ill with HPS.
The virus is often deadly but infection is very rare, and potential exposures occur much more often than infection, Chiu said. The virus is not spread by infected humans or by other animals. Furthermore, the virus does not survive long in dust after the mice that carry it have been eradicated, Chiu said.
Hantaviruses infect people when they are inhaled. If the virus reaches your lungs, it can infect the cells that line the tiny blood vessels in the lungs, causing them to become “leaky.” The leaky blood vessels allow fluid to fill the lungs making it difficult to breathe.
The majority of Hantavirus infections occur in males and in individuals between the ages of 20-40 4. Trappers, hunters, forestry workers, farmers, and military personnel have a higher risk of contracting the disease 2 4.
And even though 15-20 percent of deer mice are infected with hantavirus, Cobb explains, it's a rare disease for humans to contract, mostly because the virus dies shortly after contact with sunlight, and it can't spread from one person to another.
Hantaviruses in the Americas are known as “New World” hantaviruses and may cause hantavirus pulmonary syndrome (HPS). Other hantaviruses, known as “Old World” hantaviruses, are found mostly in Europe and Asia and may cause hemorrhagic fever with renal syndrome (HFRS).
Hantavirus enters your body when you inhale virus particles from infected rodent urine, droppings, or saliva. The virus affects the heart, lungs, and kidneys, reducing their ability to function. The virus also enters the bloodstream, where it continues to spread and cause further organ damage.
In addition, there are no reports of hantavirus infection in humans in Australia.
Hantavirus: Once thought to be rare this disease has been identified in rodents across Australia. This serious and potentially fatal disease is spread through inhalation of dust that contains urine, saliva, or droppings.