Composed of a sugar molecule which is also produced naturally in the body, it generally dissolves and is excreted by the body in six to nine months. And if a client wants to get rid of it sooner, the area can be injected with an enzyme which will dissolve the filler completely within two hours.
Hyaluronic acid-based (HA) fillers can be dissolved using an enzyme called hyaluronidase, or Hyalase. The solution works by breaking up the bonds that hold the HA molecules together and encourages the body to reabsorb them.
This isn't permanent and can be treated with dissolving all of the filler, refilling the lips again subtly after two weeks and in some cases the use of Botox or skin tightening treatments to tighten up the skin around the mouth again and reduce any remaining fine lines.
Hyaluronidase – the enzyme that dissolves filler
In the body, both the natural hyaluronic acid and the hyaluronic acid injected in the form of fillers will degrade over time by reactive oxidative species (free radicals) and by an enzyme produced in the body called hyaluronidase.
"Theoretically, all filler has the ability to migrate," says Dr. Diamond. "That is why it is so imperative that non-surgical injectable services are performed by experts with the anatomical knowledge to prevent this from happening.
Can your face go back to normal after fillers? Many patients fear that when the filler wears off, they will look worse than before. Though fillers may stretch your skin, it is elastic enough to revert to its original form before your treatment. However, anything that's too much is also not good for you.
To avoid migration from overfilling, take a slow and steady approach, says Dr. Durairaj. "The typical lip filler syringe is expected to last at least one year, and mostly [injectors are] finding that it lasts a lot longer than that.
Massage can encourage the filler to be broken up by the body more quickly. But in practice this still takes a long time (like weeks of daily vigorous massage) to improve the outcome. This may also spread the product over a larger area causing more problems.
Deep injections may last as long as 12 months, and newer products on the market may last up to two years.
So while the body naturally breaks them down over time, there is a way to speed up the process: Injections of hyaluronidase. Hyaluronidase is what the body produces naturally to break down fillers, so by injecting more, it allows the lips to regain natural shape quicker, usually going down within 3-4 days.
For some, getting their fillers dissolved is painful, whereas for others it doesn't hurt as much as getting filler in the first place. Numbing solution or anaesthetic is applied before the filler dissolving enzyme is used, in order to make it as comfortable as possible.
If the filler is in a location further away from direct blood flow than other locations, then this means that cells that secrete hyaluronidase will not be able to reach the hyaluronic acid gel, and will therefore be unable to dissolve it.
You won't be able to have a dermal filler treatment immediately after your Hyalase treatment, as the product needs time to dissolve the older filler and for your lips to settle into their natural shape and projection. Expect to wait for 10 to 14 days before new filler can be administered.
It is not likely for Hyaluronidase to migrate to other region of the face and cause volume loss. There might be a temporary natural HA loss but the body replenishes it within few days. Also, having several dissolving sessions with low dose is more ideal.
Hyaluronidase doesn't spread so you won't have a problem with having it injected into your top lip while avoiding the marionette lines, which you do like.
How far does 1 ml of dermal filler go? Traditionally cosmetic practitioners would inject 1mL of dermal filler into one area of the face. For example, 1mL lip filler and 1mL cheek filler, however, only 1ml of filler can enhance your entire face.
However, it must be stressed, however, that filler does not migrate from one area of the body to another. What being discussed on social media is simply so-called migration of a few millimeters within the same anatomical regions where it was injected.
Although extremely rare, dermal fillers are able to migrate within the skin if consistent and adequate pressure is applied to them. For this reason, we advise patients not to get a facial, massage (on the treated skin), or microdermabrasion for the first two weeks following their filler injections.
Generally, any lumps or bumps that appear after fillers will disappear on their own within one to two weeks. Give the treatment a couple of weeks to improve, applying ice regularly.
There isn't any known evidence that routine kissing will cause more rapid breakdown of the product or move the filler. However, very heavy manipulation of the lips isn't a great idea either soon after filler injections.
Filler migration is the movement of a dermal filler from its injection site to another area of the body. While it is possible for fillers to migrate, this side effect is extremely rare and can be avoided by choosing a qualified injector.
The age that most women get dermal fillers is between 40 and 54. According to the American Society of Plastic Surgeons Annual Report, this age range received over a million soft tissue filler treatments in 2016, good for 17 percent of all procedures.