Do not take more than 100 micrograms (4,000 IU) of vitamin D a day as it could be harmful. This applies to adults, including pregnant and breastfeeding women and the elderly, and children aged 11 to 17 years. Children aged 1 to 10 years should not have more than 50 micrograms (2,000 IU) a day.
Taking 60,000 international units (IU) a day of vitamin D for several months has been shown to cause toxicity. This level is many times higher than the U.S. Recommended Dietary Allowance (RDA) for most adults of 600 IU of vitamin D a day.
Extremely high doses—around 10,000 IU a day—can trigger calcium deposits in the blood vessels, which can lead to clots that cause heart attacks. The IOM panel recommended no more than 4,000 IU of vitamin D daily to avoid these potential problems.
Phenobarbital, phenytoin, and other anticonvulsant medications -- These medications may accelerate the body's use of vitamin D. Mineral oil -- Mineral oil also interferes with absorption. In addition, Vitamin D may enhance the effects of doxorubicin , a medicine used to treat a variety of cancers.
Vitamin D supplement may have moderate or no effect on the dosage requirement or side effects of pravastatin, rosuvastatin and pitavastatin. Since vitamin D has mild HMG-CoA reductase activity, it will work synergistically with all statins.
Tell your doctor right away if any of these signs of high vitamin D/calcium levels occur: nausea/vomiting, constipation, loss of appetite, increased thirst, increased urination, mental/mood changes, unusual tiredness. A very serious allergic reaction to this drug is rare.
Our only hard recommendation: Avoid supplementing with vitamin D at night. There's evidence that vitamin D can suppress melatonin—which is bad news for your sleep quality.
You may suffer from constipation, nausea, abdominal pain, vomiting, headache, aching muscles or bone, fatigue, thirst, sweating, vertigo, anorexia, somnolence or frequent urinating.
For most adults, vitamin D deficiency is not a concern. However, some groups — particularly people who are obese, who have dark skin and who are older than age 65 — may have lower levels of vitamin D due to their diets, little sun exposure or other factors.
While vitamin D itself is unlikely to be causing your anxiety, that doesn't mean it can't, and the activities that you do to help increase vitamin D are valuable for your anxiety anyway. Getting outside will help you get what vitamin D you can, although there are also nutritional supplements available.
Norman also lists 36 organ tissues in the body whose cells respond biologically to vitamin D. The list includes bone marrow, breast, colon, intestine, kidney, lung, prostate, retina, skin, stomach and the uterus. According to Norman, deficiency of vitamin D can impact all 36 organs.
Some people may need a higher dose, however, including those with a bone health disorder and those with a condition that interferes with the absorption of vitamin D or calcium, says Dr. Manson. Unless your doctor recommends it, avoid taking more than 4,000 IU per day, which is considered the safe upper limit.
Taking supplements providing more than 4,000 IU daily is not recommended unless under a health care provider's supervision, though, according to MedlinePlus, most toxicity occurs with doses above 10,000 IU daily. Symptoms of vitamin D toxicity mostly include digestive, muscular and neurological ones: Nausea. Vomiting.
Vitamins D, E and K
“Studies have shown that a person's absorption of Vitamin K may be reduced when other fat-soluble vitamins such as Vitamin E and Vitamin D are taken together,” says Dr. Chris Airey, M.D. “It's advised that you take these vitamins at least 2 hours apart to maximize your absorption.”
There are quite a few differences between vitamin D and vitamin D3, but the main difference between them is that vitamin D is a fat-soluble vitamin that regulates calcium and phosphorous levels in the body, whereas the vitamin D3 is the natural form of vitamin D produced by the body from sunlight.
What's more, taking too much vitamin D can also negatively impact our health as well as our joint pain because our body simply can't cope! If toxic levels of vitamin D build up in the body it can interfere with your body's absorption of calcium.
Vitamin D and cholesterol: What to know. The connection, if any, between vitamin D and cholesterol is unclear. Some research suggests that vitamin D supplements may improve cholesterol levels. However, others indicate that vitamin D has no effect on low-density lipoprotein (LDL) cholesterol.
Though there have been many studies done on vitamin D and cholesterol, there's not enough evidence to say for certain if vitamin D helps lower cholesterol. A 2012 study published in Arteriosclerosis, Thrombosis, and Vascular Biology found that supplementing with vitamin D did nothing to lower participants' cholesterol.
Thus, it is clear that Vitamin D supplementation has a role in the regulation of blood pressure and that it should be supplemented with the antihypertensive drugs to the patients with hypertension.
Vitamin D is necessary for our health, especially our bone health and immune system. While it is possible to take enough vitamin D once a week to keep yourself balanced, the best results were found to be a lower dose (1,000-2,000 IUs or 25-50 mcg ) taken daily.