A person may experience withdrawal symptoms due to chemical changes in the brain. The body adjusts to changes that an antidepressant such as Zoloft may cause. Stopping or reducing the antidepressant can throw the brain into a state of imbalance. This can have a physical and mental impact.
“There are a lot of biochemical mechanisms in the body to keep our neurotransmitters stable,” he says. “Taking an SSRI perturbs that system.” Withdrawal symptoms might actually be the result of the body struggling to recover its natural serotonin balance, he adds, “desperately trying to get things back to normal.”
Withdrawal symptoms usually come on within 5 days of stopping the medicine and generally last 1 to 2 weeks. Some people have severe withdrawal symptoms that last for several months or more. See your doctor if you get severe withdrawal symptoms after you stop taking antidepressants.
Hall-Flavin, M.D. Antidepressant withdrawal is possible if you abruptly stop taking an antidepressant, particularly if you've been taking it longer than four to six weeks. Symptoms of antidepressant withdrawal are sometimes called antidepressant discontinuation syndrome and typically last for a few weeks.
When experiencing withdrawal symptoms or antidepressant discontinuation syndrome, increasing physical exercise or changing the diet to include more fresh food may help ease symptoms by making a person feel reinvigorated and less lethargic.
Antidepressant discontinuation syndrome, also called antidepressant withdrawal, occurs when a person abruptly stops taking antidepressant medication. Many people who experience antidepressant withdrawal feel like they have the flu or a stomach bug. They may also experience disturbing thoughts or images.
Initial symptoms appear in some individuals within 1-3 days following an abrupt discontinuation of the medication. The symptoms typically last 1-3 weeks and will typically peak within the first week. Symptoms can be relieved within 24 hours by restarting the antidepressant medication.
Discontinuing an antidepressant medication usually involves reducing your dose in increments, allowing two to six weeks or longer between dose reductions. Your clinician can instruct you in tapering your dose and prescribe the appropriate dosage pills.
For people with chronic or severe depression, medication may be needed on a long-term basis. In these cases, antidepressants are often taken indefinitely. That is, in part, because depression is not an illness that can be cured.
If the symptoms develop later or gradually, they may constitute a relapse of the depression. Ultimately, these withdrawal symptoms will improve with time, but they can be unpleasant for days and possibly even weeks. In time, the brain readjusts and people should experience a return to their normal state.
Overview. Antidepressant withdrawal can make you feel edgy and out of sorts. You may feel like you have the flu (sluggish with a headache and nausea), have trouble sleeping and concentrating, and experience anxiety and even thoughts of suicide.
Agitation, restlessness or anxiety can result from the stimulating effect of certain antidepressants. Although having more energy can be a good thing, it may mean you can't relax or sit still even if you want to.
Do I have to take antidepressants forever is a question that some ask as they struggle with depression. This is one of the more common myths associated with the condition. You do not need to take antidepressants forever nor do you need to get a prescription from a counselor or therapist.
Someone coming off antidepressants after 10 years, or a higher dose, might have to gradually reduce their dose for several months. A tapering schedule can involve cutting your current dose by 10% and up to 50% each week — depending on the half-life of the medication — and see how you feel for the next 2 to 4 weeks.
One possible way to get relief is to take a dose of Prozac (fluoxetine) along with medications like Zoloft (sertraline) and Lexapro (escitalopram) that you are trying to taper. Your symptoms will likely go away within a few hours. And because of Prozac's long half-life, it will help smooth out the taper.
A sudden change in dose of antidepressants can cause the serotonin levels to fall, producing withdrawal symptoms. Around 20% of people taking antidepressants experience withdrawal symptoms when they stop or reduce their dose. The symptoms are sometimes similar to those of depression.
If you decrease your daily calorie intake as a result, you could potentially lose weight by stopping your antidepressants. On the other hand, if you experience loss of appetite with depression, and your depression comes back after stopping antidepressants, you may also lose weight.
Different antidepressants will have different discontinuation side effects. Psychiatric symptoms of discontinuation such as anxiety and agitation, crying spells, or irritability are also sometimes misdiagnosed as a depressive relapse.
The majority of people taking the most commonly prescribed antidepressants—selective serotonin reuptake inhibitors (SSRIs)—improve substantially. But sometimes, SSRIs go beyond improving mood and make a person feel too little emotion. "Some people feel like they've lost the richness of daily life," says Dr.
Usually, common antidepressant overdose side effects include: Nausea and/or vomiting. Dilated pupils. Vision problems.
Stopping antidepressants suddenly is not dangerous but you could get withdrawal symptoms or become unwell again if you make a sudden change. If you can, stop your antidepressant when you have felt better for the last six months on medication. Plan in advance to cut down your dose gradually.
Clinicians generally recommend staying on the medication for six to nine months before considering going off antidepressants. If you've had three or more recurrences of depression, make that at least two years.
Long-term antidepressant users are risking permanent damage to their bodies, according to leading medical experts. Dr Tony Kendrick, a professor of primary care at the University of Southampton, says more urgent action needs to be taken to encourage and support long-term users to come off the medication.