Freeman–Sheldon syndrome is a very rare form of multiple congenital contracture syndromes and is the most severe form of distal arthrogryposis. It was originally described by Ernest Arthur Freeman and Joseph Harold Sheldon in 1938. As of 2007, only about 100 cases had been reported in medical literature.
People with Freeman-Sheldon syndrome may have difficulty swallowing (dysphagia), a failure to gain weight and grow at the expected rate (failure to thrive), and breathing complications that may be life-threatening. Speech problems or hearing impairment can also occur in people with this disorder.
Freeman-Sheldon syndrome (FSS) or “whistling face syndrome” is an exceptionally rare disorder present before birth (congenital) that primarily affects muscles of the face and skull (craniofacial muscles) but frequently involves problems with joints of the hands and feet.
Sheldon-Hall syndrome can be caused by mutations in the MYH3, TNNI2, TNNT3, or TPM2 gene. These genes provide instructions for making proteins that are involved in muscle tensing (contraction).
His obsessive-compulsive tendencies, including his inability to accept change in his life, his multiple phobias (towards germs, birds, etc.), and his hypochondria.
Apart from OCD, psychologists have studied Sheldon's behaviour and have also diagnosed him of Narcissistic personality disorder, Borderline personality disorder and Paranoid personality disorder. Did we miss any of Sheldon's OCD symptoms?
Creators of the show have said Sheldon is not on the autism spectrum but Jim Parsons has mentioned how his character shows some Asperger-like characteristics. Symptoms include finding it hard to understand and relate to others, and Sheldon does find it difficult to sympathise with other characters.
Aside from the narrative tease, another interesting revelation from the clip is Sheldon's significantly deeper voice, establishing that he has officially entered puberty. This means that CBS can no longer have the 14-year-old Ian Armitage continue playing Sheldon as a 12-year-old.
(It was the only award for the series.) In 2009, Paul Collins took a close look at Sheldon's hilarious, geeky, gawky character and argued that although the series never describes him as such, Sheldon is the first sitcom star to have Asperger's syndrome.
Most people with Char syndrome have a characteristic facial appearance that includes flattened cheek bones and a flat nasal bridge (the area of the nose between the eyes).
Ayme-Gripp syndrome
The facial features are often described as "Down syndrome-like" and include brachycephaly, flat facial appearance, short nose, long philtrum, narrow mouth, and low-set and posteriorly rotated ears. Hearing loss is often congenital.
A minority (10% to 20%) of Turner's syndrome girls has mild to moderate mental retardation and up to 70% have learning difficulties. In general, they have learning disabilities, attention deficit, and greater impairment on performance than verbal IQ testing.
Amy Farrah-Fowler, “The Big Bang Theory” While Sheldon Cooper may be the favorite among most viewers of “The Big Bang Theory,” those in the Aspie community seem to favor Sheldon's long-time girlfriend, Amy Farrah Fowler. Amy, an Aspie, tends to present a more balanced view of those on the autism spectrum.
Some argue that Sheldon's behavior is simply a result of his high intelligence and unique personality, and that he does not display all of the traits commonly associated with autism. However, others argue that Sheldon's behavior is too consistent with autism to be a coincidence.
IQ Score: 187
He is truly a genius, and Sheldon Cooper's IQ literally proves it. He attended college at the age of 11 (as seen in Young Sheldon), is brilliant enough to avoid being fired for his inappropriate actions, and of course, is a Nobel Prize winner.
Because of The Big Bang Theory, fans of the series know that Sheldon's dad dies when he is 14, about a year after Sheldon discovers his father having an affair. Season 7 seems the most likely point for George's death.
By the time the events of The Big Bang Theory started, George was already long dead, preventing him from physically appearing in the series, although he made a creative cameo through its one-time crossover with Young Sheldon.
It's the actor (Jim Parsons) - he has OCD and apparently a terrible hand-washing problem. Thus, his hands always look inflamed.
While adult Sheldon might want to pretend that he named his son after the actor who played Spock, fans of The Big Bang Theory will know the name Leonard was actually a tribute to Leonard Hofstadter, Sheldon's roommate for more than a decade, and the best friend he ever had.
Sheldon Cooper's NPD tendencies are clear in that he feels he is superior to others in many different ways, especially intellectually. He looks down on many people and feels he deserves to be recognized for his cognitive abilities.
Savant syndrome is a rare condition in which persons with various developmental disorders, including autistic disorder, have an amazing ability and talent. The condition can be congenital (genetic or inborn), or can be acquired later in childhood, or even in adults.
I have a thyroid condition, which means that's an immunocompromised situation.” Along with exhaustion, Bialik said that she felt a tightness in her chest that “doesn't feel good at all”. Bialik is best known as Amy Farrah Fowler from The Big Bang Theory.
Separations, disagreements, and rejections—real or perceived—are the most common triggers for symptoms. A person with BPD is highly sensitive to abandonment and being alone, which brings about intense feelings of anger, fear, suicidal thoughts and self-harm, and very impulsive decisions.
People with borderline personality disorder may experience intense mood swings and feel uncertainty about how they see themselves. Their feelings for others can change quickly, and swing from extreme closeness to extreme dislike. These changing feelings can lead to unstable relationships and emotional pain.
Beth Harmon (Anya Taylor-Joy), whilst not declared autistic, was heavily coded as such. And rather than playing into stereotypes (one can just imagine how a lazy interpretation of an autistic chess prodigy would come across), Taylor-Joy gives the role complex and dynamic layers.