Use of traditional antihistamines has until recently been associated with a number of undesirable side-effects, the most troublesome of which is sedation.
You shouldn't take prescription antihistamines if you also are taking certain other prescription medicines. These include erythromycin (an antibiotic), or certain medicines used to treat fungal infections. These include itraconazole or ketoconazole.
“The most common side effects you tend to see are fatigue, headaches, and dry mouth,” says Shih. If you're someone for whom the benefits of regular antihistamine use far outweighs the occasional minor side effect, longterm use is safe for most adults and children, he adds.
Long term use of some antihistamines may increase your risk of dementia. Diphenhydramine (Benadryl®) blocks the effects of a neurotransmitter called acetylcholine. This neurotransmitter is vital for memory and learning.
Is it safe to take Zyrtec every day? Yep. "When taken in the recommended doses, antihistamines can be taken daily. This is especially true with Zyrtec, since it doesn't show decreasing effectiveness if used daily," says Sima Patel, MD, an allergist at New York Allergy & Sinus Centers.
Side effects of antihistamines
sleepiness (drowsiness) and reduced co-ordination, reaction speed and judgement – do not drive or use machinery after taking these antihistamines. dry mouth. blurred vision. difficulty peeing.
Claritin and Zyrtec are effective and safe for most people with minor allergies. However, as with all medications, there may be some side effects. Loratadine—present in Claritin—may not be safe for people with severe liver conditions.
Claritin comes highly recommended by Dr. Fineman as an effective antihistamine. This medication comes in a wide variety of formats, including tablets, gel capsule pills, chewables and orally-disintegrating tablets (for those who have trouble swallowing pills).
Summary. Natural antihistamines may help you control your seasonal allergies. Common ones are stinging nettle, vitamin C, quercetin, butterbur, bromelain, and probiotics. Some alternative practices—such as acupuncture, nasal irrigation, and exercise—may also help you manage symptoms.
For the average healthy adult, elimination half-life ranges from 6.7 to 11.7 hours. So between 6 to 12 hours after taking Benadryl, half the drug will be eliminated from the body. Within two days, the drug will be completely gone from the body.
Unrelated to the immune system, histamine is also produced in the brain, where it plays an important part in feeling awake. Antihistamines used to treat respiratory symptoms can get into the brain and interrupt this work, making you feel drowsy.
Greg Panico, a spokesman for Janssen Pharmaceutica, which is owned by Johnson and Johnson, said that the withdrawal was a voluntary business decision. “The decision to voluntarily discontinue it recognises that the allergy marketplace is crowded with a number of other drugs,” Mr Panico said.
Some elderly people may have higher risk of side effects because of poor kidney function. The drowsiness and fatigue which may occur in a small percentage of patients may be more of a problem for the elderly because of the increased risk of bone fracture if they fall.
So what can older adults safely take for allergy relief? Wozniak: Newer antihistamines such as Claritin® (loratadine) and Allegra® (fexofenadine) tend to be safer and better tolerated.
For many people with allergies, symptoms are the worst around 4 a.m. to 6 a.m. Taking an antihistamine at bedtime may help you or your child feel better in the morning during allergy season.
You should not use Zyrtec-D if you have narrow-angle glaucoma, severe high blood pressure (hypertension), severe coronary artery disease, if you are unable to urinate, or if you are allergic to hydroxyzine (Atarax, Vistaril). Do not use this medicine if you have taken an MAO inhibitor in the past 14 days.
Tolerance is not a problem. Rarely, they can cause acute self-limited liver injury. One study has reported a more serious long-term effect, a 3.5-fold increase in the risk of gliomas, a common type of brain tumor in patients with long-term antihistamine use for allergic conditions.
"Itching can occur within one-two days of stopping Zyrtec or Xyzal after long term daily use (months to years). It usually lasts a few days and then resolves. The intensity of the itching can be from mild to severe. Occasionally, a brief burst of oral steroids may be needed to help the patient get off the drug.
Second-generation antihistamines are effective in elderly patients with allergic rhinitis in drops and oral forms. Their safety is based on a relatively low rate of passage across the blood–brain barrier.
Adults—5 to 10 milligrams (mg) once a day. Children 6 years of age and older—5 to 10 mg once a day. Children 4 to 6 years of age—2.5 mg once a day, up to a maximum of 5 mg once a day or 2.5 mg twice a day. Children and infants up to 4 years of age—Use is not recommended .
Sometimes this effect is mistakenly called an addiction; no, you're not becoming addicted to your allergy medication, but your tissues can become used to the effect of the medication. The result is that, when the dose wears off, you can feel a little worse.
Citrus Fruits – Vitamin C (ascorbic acid) is an antioxidant that prevents oxidative stress in the body and is also a natural antihistamine. Consuming adequate amounts of Vitamin C from citrus fruits such grapefruits, oranges, lemons and kiwis can also help fight infections.