What is the Williams syndrome associated with?

What causes Williams syndrome? Williams syndrome is caused by a partial deletion of up to 28 genes on chromosome 7. This means that a section of genetic material on chromosome 7 is missing. It is believed that some of these genes are involved in the production of elastin.

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What disorders are related to Williams syndrome?

Medical problems involving vision or hearing, including sensitivity to sound (hyperacusis), are frequently associated with Williams syndrome. In addition, problems with the digestive tract and the urinary system are also possible. Obesity or diabetes can develop in adulthood.

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What are people with Williams syndrome known for?

People with WS may have mild to moderate delays in their cognitive development (ability to think and reason) or learning difficulties. They also may have a distinctive facial appearance, and a unique personality that combines over-friendliness and high levels of empathy with anxiety.

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What is the main cause of Williams syndrome?

Williams syndrome is caused by not having a copy of 25 to 27 genes on chromosome number 7. In most cases, the gene changes (mutations) occur on their own, either in the sperm or egg that a baby develops from. However, once someone carries the genetic change, their children have a 50% chance of inheriting it.

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What are 3 symptoms of Williams syndrome?

Symptoms of Williams syndrome include:
  • Chronic ear infections and/or hearing loss.
  • Dental abnormalities, such as poor enamel and small or missing teeth.
  • Elevated calcium level in the blood.
  • Endocrine abnormalities: hypothyroidism, early puberty and diabetes in adulthood.
  • Farsightedness.
  • Feeding difficulties in infancy.

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Williams syndrome - an Osmosis Preview

18 related questions found

Does Williams syndrome get worse with age?

There is also evidence of accelerated ageing among individuals with Williams syndrome. An early onset of hearing loss is common and may coexist with hyperacusis (aversion to loud noises). There may also be premature greying of hair.

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Does Williams syndrome affect behavior?

The behavioral symptoms of the syndrome include over-friendliness, increased empathy (the ability to understand the feelings of others), cognitive (mental) disorders, highly developed language skills, disrupted ability to recognize danger in social situations, and high levels of non-social stress (stress that is not ...

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Is Williams syndrome a form of autism?

Autism and Williams syndrome are genetically based neurodevelopmental disorders that present strikingly different social phenotypes. Autism involves fundamental impairments in social reciprocity and communication, whereas people with Williams syndrome are highly sociable and engaging.

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Are people with William syndrome smart?

Most individuals with Williams syndrome have a degree of intellectual disability, ranging from mild to severe. Research studies have suggested that IQ scores for children with Williams syndrome range from 40 to 112, with a mean IQ score of 68 which equates to a mild intellectual disability (average IQ is 100).

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How many people have Williams syndrome in Australia?

It affects approximately 1 in 10000 Australians. There are many symptoms that vary from person to person, but they each share a very social and friendly disposition and have a deep affinity with music.

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Can someone with Williams syndrome have kids?

Can people with Williams Syndrome have a child/children of their own? There are no significant physical reasons why people with Williams Syndrome cannot conceive normally, but their own health may pose a potential risk, particularly if they have a heart condition.

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Can Williams syndrome be cured?

There is no specific cure for Williams syndrome, so care is focused on treating specific symptoms or cardiovascular problems. Children with Williams syndrome who have a heart defect may need heart catheterization or surgery to repair the problem, including: ballooning or stenting of blood vessels.

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Is William syndrome hereditary?

The deletion can occur in either the egg or the sperm. It is likely that in most families, the child with Williams syndrome is the only one to have the elastin gene condition in his or her entire extended family.

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What are the behavioral issues of Williams syndrome in adults?

Behavioural difficulties include: lack of social inhibition/discrimination, attention deficits, fears phobias, generalized anxiety (often related to health and illness), preoccupations obsessions (e.g. certain types of machinery e.g. lawn mowers, washing machines) and perseverative behaviour (doing or saying the same ...

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Is Williams syndrome progressive?

Williams syndrome is a progressive disorder with multisystem involvement.

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Is Williams syndrome associated with ADHD?

The most common psychiatric disorders found in Williams syndrome have been reported mainly in children and include Attention-Deficit/Hyperactivity Disorder (ADHD) in 65%, Specific Phobia in 43%, and Generalized Anxiety Disorder (GAD) in up to 24% of cases.

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Why are Williams syndrome people so happy?

And they found that people with Williams syndrome have a lot more oxytocin than everybody else, and that it fluctuates wildly in the brain. As a result, they feel this biological impulse to love all the time.

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Do people with Williams syndrome talk a lot?

The low I.Q., however, ignores two traits that define Williams more distinctly than do its deficits: an exuberant gregariousness and near-normal language skills. Williams people talk a lot, and they talk with pretty much anyone [p.

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How long is the life span of someone with William syndrome?

Patients usually have a normal life expectancy. Some patients may have a reduced life expectancy. This is due to complications related to the heart and kidney. There is no cure for Williams syndrome.

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Are people with Williams syndrome always happy?

Williams syndrome is called the happy syndrome because people with this condition often have outgoing, friendly personalities and tend to be very social. They may have a unique ability to connect with others and form strong bonds, making them appear very happy and engaging.

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Do kids with Williams syndrome talk?

Communication difficulties: Most children with Williams syndrome develop speech skills later than other children their age. With intervention, most children develop the ability to communicate wants and needs effectively. In fact, for many children with Williams syndrome, expressive language may be a relative strength.

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Do kids with Williams syndrome sleep?

Beyond infancy, findings have consistently indicated that children with WS have more sleep problems than age-matched TD children, including sleep anxiety, bedtime resistance, sleep onset delay, frequent night waking, general restlessness, and excessive daytime sleepiness [10, 11, 41,42,43,44,45,46,47].

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What do people with Williams syndrome tend to look like?

Young children with Williams syndrome have distinctive facial features including a broad forehead, a short nose with a broad tip, full cheeks, and a wide mouth with full lips. Many affected people have dental problems such as small, widely spaced teeth and teeth that are crooked or missing.

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What is the personality of someone with mild Williams syndrome?

The personality of individuals with Williams syndrome involves high sociability, overfriendliness, and empathy, with an undercurrent of anxiety related to social situations.

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Can a person with Williams syndrome live alone?

A degree of mental retardation is present in the majority of people with the disorder, and while some adults with Williams-Beuren syndrome have the ability to live independently, completing vocational or academic school and living on their own or in supervised homes, the majority of people with this disorder live with ...

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