You're more likely to have nausea when you first start Ozempic treatment or after your doctor increases your dose. For most people, this side effect goes away within a few days or weeks.
The most common side effect with Ozempic is nausea and occurs in about 15% to 20% of people. Others include vomiting (5% to 9%), diarrhea (8%), stomach-area pain (6% to 7%), and constipation (3% to 7%).
Semaglutide (Ozempic, Wegovy, Rybelsus) can cause side effects that some people are unable to tolerate. Following dosing guidelines can help manage these side effects. Nausea, vomiting, and diarrhea are the most common semaglutide side effects. But they usually subside after a few weeks of using the medication.
Ozempic can cause nausea and vomiting if taken after eating foods high in fat or sugar. It is recommended that you take Ozempic before meals, rather than after, to minimise any potential side effects from eating high-fat or high-sugar foods.
Still, Ozempic and other GLP-1 medications will be most effective for weight loss and blood sugar control when combined with a healthy diet and regular exercise. Generally, eating healthy foods and avoiding foods high in sugar, calories, and unhealthy fats while taking Ozempic helps.
Ozempic and its sister medication, Wegovy — approved for weight loss for people who are obese or overweight with weight-related medical conditions — are considered long-term or lifelong treatments.
Lean protein sources from eggs, low-fat cheese, Greek yogurt, chicken, turkey, fish, nuts, tofu, and beans are all excellent ways to bulk up on protein while eating healthy if you take Ozempic. Lean proteins usually require little to no insulin (if you're on insulin), and are a great building block of a healthy meal.
Ozempic works by adjusting the way your body processes glucose (sugar). This can lead to slower digestion, which means food stays in your stomach longer as it's being broken down. As your stomach works on digesting, it produces additional gas, which can lead to that uncomfortable bloating feeling and stomach pain.
You start feeling those usual hunger pangs again, and consequently, you may start eating more to satisfy that hunger. An increase in your consumption can lead to the regaining of weight that was lost. A 2022 study found that most individuals gain weight back a year after stopping the medication.
The drugs may also affect your sleep, which can tank your energy levels. And adverse GI events — the most commonly listed side effect of the drugs — can easily cut into your sleep, making you feel tired.
On average, a user can lose about 3 to 5% of their body weight after using Ozempic for a month regularly. This equates to about 4 to 6 pounds on average. Using a higher potency of the drug may result in more weight loss, but it isn't recommended that you start taking it right away.
You may need a higher dosage of Ozempic
The same holds true for Ozempic's weight loss results. People taking higher doses of Ozempic tend to lose more weight. In the landmark study we cited above, people lost 7% of their body weight, on average, within a year and a half of taking 1mg of semaglutide.
If you stop taking Ozempic, the weight you lost will likely return, fast. People who ceased use of semaglutide gained back, on average, a full two-thirds of the weight they had lost on the drug within one year, according to an August 2022 study, the Wall Street Journal reports.
Can I drink alcohol while using Ozempic? The short answer is yes: you can drink alcohol while taking Ozempic. In the U.S., where Ozempic is created and distributed from, the Food and Drug Administration has not provided any specific disclaimers on mixing Ozempic and alcohol [1].
A person can stay on Ozempic® so long as they are tolerating the medication and it is deemed appropriate by their treating provider. There is no specific time frame when someone should stop taking Ozempic as it is a medication that is intended for chronic (long-term) use.
Ozempic is also used off-label for weight loss. In particular, it can help reduce the amount of belly fat. This is because Ozempic works by making you feel fuller for longer, which can help you resist overeating by controlling cravings and hunger.
So, on average, with the recommended starting Ozempic dose of 0.25 mg, a 500 to 1000 calorie reduced diet, and exercise 3 times a week, you can expect to lose 3-5 pounds in the first month of treatment, which works out to about 3% of body weight for most overweight or obese individuals.
Although there are no specific rules or diets to accompany using Ozempic, reducing the number of processed foods in your diet whilst increasing fibre-rich whole foods can help with lowering your overall calorie intake.
(No member of the Kardashian family has publically said they use Ozempic.) Ozempic is the brand name for the medication semaglutide, which treats diabetes by balancing out hormones like insulin.
However, doctors have now issued a warning about “Ozempic face,” a possible side effect of using the drugs both as a weight-loss method and without the proper medical supervision, as users have shared their experiences with accelerated ageing.